Scientist I, gRNA Analytical Development Somerville, Massachusetts, United States

Company: Tbwa Chiat/Day Inc
Location: Somerville
Posted on: November 1, 2024

Job Description:

Scientist I, gRNA Analytical DevelopmentSomerville, Massachusetts, United StatesMinimum Qualifications:

• BS in analytical chemistry, biochemistry, or relevant discipline with 8+ years of relevant experience, or M.S. with 6+ years relevant industry experience, or PhD with 1+ years industry experience.
• The application of a diverse set of analytical assays, with strong background in LC-MS (required) and HPLC preferable.
• RNA or Oligonucleotide analytical chemistry and biophysical techniques (required), preferably in biopharmaceutically relevant systems.
• Analyzing and interpreting written material, in various forms including tables and spreadsheets, as well as quantitative and qualitative data.
• Writing clear and concise reports and memos.
• A high level of personal and spatial organization.
• Strong interpersonal and communication skills.
• A learning and betterment mindset.You are interested in---
  • Advancing existing and establishing new methods using mass spectrometry and HPLC to characterize RNA molecules (oligonucleotides).
  • Representing the Analytical Development team in cross-functional meetings, presenting results and providing scientific input as needed.
  • Participating in in-depth investigations, including orthogonal method evaluation, understanding oligonucleotide stability, and characterizing impurities in a CMC setting.
  • Exploring new technology and software to strengthen and streamline oligonucleotide characterization workflows.
  • Maintaining external awareness of advances in the field through keeping updated on relevant publications, attending conferences and workshops.
  • Effectively collaborating within the Analytical team and with other functional teams.
  • Using scientific and technical expertise for instrument maintenance and troubleshooting.
  • Training and mentoring junior scientists as needed.
  • Performing assays, analyzing, interpreting, and reporting results in appropriate format (ELN, analytical reports, and presentations).
  • Performing additional duties and responsibilities as required.About You:You have an interest in developing and implementing RNA molecule characterization assays. You are able to work well independently or as part of a team, have impeccable attention to detail, and enjoy working in a fast-paced environment.Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence.Company Summary:Tessera Therapeutics is pioneering Gene Writing-a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy.More about Tessera Therapeutics:Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate.
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Keywords: Tbwa Chiat/Day Inc, East Providence , Scientist I, gRNA Analytical Development Somerville, Massachusetts, United States, Other , Somerville, Rhode Island